Keep in mind that probiotics are considered dietary supplements and are not FDA-regulated like drugs. It should be noted that many of the possible health benefits of probiotics still require more scientific research to be proven Curiously, these compounds are also responsible for the FODMAP indigestion that appears to account for non-Celiac gluten intolerance. Where are the prebiotics (that feed beneficial bacteria) in the American diet? Mostly wheat and onions, with small amounts from garlic and bananas. (1992) indicate that when the product containing the probiotic is not longer consumed, the added bacteria are rapidly washed out of the colon. Next, the bacteria would need to compete for nutrients and ecological sites of colonization with a previously established microbial flora comprising several hundred other bacterial species. This would probably compromise its chances of survival. The probiotic is likely to be in some sort of stressed state due to its encounters with the adverse conditions (in earlier digestion). For increased persistence the probiotic may need to adhere to the intestinal epithelium. The probiotic microorganism needs to establish in the colon and, preferably, become active. The active bacteria in any fermented food or probiotic have temporary effects in the context of well established pathogenic microbiota or food habits that don't preferentially feed the beneficial strains.įrom Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics (1995)
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